After I got my iPhone 3G a couple about 2 months ago, I had no other choice but to use iTunes for all the syncing, backups, music etc as Apple wants total control of what you can or can’t do with its devices (was using YamiPod previously, writeup here). :|

My loathing for it got worse as it didn’t seem to be closing gracefully on quitting besides causing software restores which all ended up with iTunes.exe taking up 100% CPU. I decided to stop swearing at it and search around for the root cause as this behaviour wasn’t replicated on my work machine and on colleague’s variety of machines.

Turns out it wasn’t iTunes, but the antivirus (NOD32 2.7) which wasn’t playing nice. After adding various iTunes paths to AMON/IMON exclusion lists, there has not been crashes or 100% CPU since (instructions on how to do this here). Guess I was cursing the wrong software but anyhow..

Just a note, this is a fairly belated post as I was having this issue with iTunes 7.x and have since upgraded to 8.0.1 which may no longer require this workaround. ;)